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  • Improved RNA interference kits launched by Imgenex  By : Stephen Jones
    RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The RNAi pathway is thought to be an ancient mechanism for protecting the host and its genome against viruses and rogue genetic elements that use double-stranded RNA (dsRNA) in their life cycles. For more details read out the following article:-
  • Regulatory T Cells (Treg)  By : Stephen Jones
    Early development and differentiation of nascent T cells inside the thymus is a complex and remarkable mechanism.These types of T-cells require a different strategy to tame their autoimmune potential. One of many immunotolerance mechanisms that immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs. For more details read out the article:
  • NF-kB Activation: Elucidating Upstream Events  By : Stephen Jones
    NF-kB (Nuclear Factor-KappaB) is a heterodimeric protein composed of different combinations of members of the Rel family of transcription factors. The Rel/NF-kB family of transcription factors are involved mainly in stress-induced, immune, and inflammatory responses. For more details read out the article:
  • GPCRs: Exploring New Paradigms  By : Stephen Jones
    As one of the largest and most diverse protein families in nature, the G-protein coupled receptor (GPCR) superfamily play important roles in a variety of biological and pathological processes such as development and proliferation, neuromodulation, angiogenesis, metabolic disorders, inflammation, and viral infection. Not surprisingly, it is one of the most targeted protein families in pharmaceutical research today(Schlyer 2006).
  • Fundamental Immunology, Basic Immunology and Allergy Immunology  By : Stephen Jones
    Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and substances that invade our systems and cause disease. For more details read out the following article:-
  • New FOXP3Δ2 (Exon 2 Deleted) Specific Antibody  By : Stephen Jones
    FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function and generally accepted to be expressed in both mouse and human CD4+ CD25+ regulatory T cells. For more details read out the article:
  • GPR83: A Novel Treg Expressed Cell Surface Marker  By : Stephen Jones
    GPR83 is a member of the Orphan-A G-Protein coupled receptor family, and has anunknown ligand. It has been previously reported in various regions of the brain, within a subset of T-lymphocytes, and by RT-PCR at low levels in heart, kidney, liver, and otherorgans. For more details read out the article:
  • Faces of DARPP-32: Master Signaling Mediator in the Brain?  By : Stephen Jones
    As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. For more detail read out the article:
  • Epigenetic and Signal Transduction Reagents  By : Stephen Jones
    IMGENEX offers over 90 Chromatin, DNA Methylation & Repair, and DNA Fragmentation-related antibodies, many of which have been cited in numerous peer-reviewed journals. Find out more details in the following article:
  • QuikChIP Chromatin Immunoprecipitation Kits  By : Stephen Jones
    The principle of the ChIP assay is simple yet the process can be technically challenging. It is with these challenges in mind that IMGENEX developed the QuikChIP Kit for chromatin immunoprecipitation. Find out more information from the following article:
  • ATM (Ataxia Telangiectasia Mutated) Antibodies from Imgenex  By : Stephen Jones
    ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. In undamaged cells it is present as a dimer or oligomer molecule in which the kinase domain is silent because associated with the FAT region of another ATM monomer. For more information about ATM read out the given article:
  • Are we "Livin" or just "Survivin"?  By : Stephen Jones
    Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article:
  • Apoptosis Programmed Cell Death  By : Stephen Jones
    Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article:
  • Akt Family: Antibodies from Imgenex  By : Stephen Jones
    Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. For more information about Akt family read out the given article:
  • Actin Antibody Available in Imgenex now  By : Stephen Jones
    Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments which are part of the contractile apparatus in muscle cells. For more details read out the article:
  • Skin Cancer  By : Aakash Shah
    Skin cancer is such a disease that can occur to any individual The medical experts till today could not specify the age group of occurrence
  • Cancer Drugs - Learning About Cancer Medication  By : M Nelson
    There are many types of cancer that people may suffer from but one thing that stays similar is the types of medication that they may be using There are many forms of medication that you may be prescribed with various types of side effect to go with each
  • Advance In Prostate Surgery Will Benefit 1 In 3 Men Over The Age Of 50  By : Samson Liu
    As they reach their fifties and beyond, one in three men will develop a condition known as Benign Prostatic Hyperplasia, or an enlarged prostate

    This very common condition can have a terrible impact on quality of life
  • Fighting Mesothelioma Cancer With Alternative Medicine  By : M Nelson
    Research in alternative medicine and conventional therapies to treat Mesothelioma cancer continues to be on the forefront to try and find a cure for this disease Until an alternative is discovered and shows promise, conventional drugs and therapies such as Alimta and other chemotherapy drugs, surgery to remove tumors, and radiation therapy will be used to slow the cancer growth
  • Hiding The Truth About Losing The War On Cancer  By : Tony Isaacs
    For well over half a century we have been promised by mainstream medicine that a cure or major breakthrough for cancer was just around the corner Every year we see promising new drugs and therapies announced
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